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3.
World Neurosurg ; 143: 295-307, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-32791223

RESUMO

BACKGROUND: Spinal epidural arteriovenous fistulas (SEAVFs) are rare lesions with a low risk of hemorrhage. Most patients with lumbosacral SEAVFs with hemorrhagic events will develop a spinal epidural hematoma from epidural venous pouches. To the best of our knowledge, we have reported the first case of a lumbosacral SEAVF presenting with remote intramedullary hemorrhage in the conus medullaris. CASE DESCRIPTION: A 56-year-old man presented with sudden-onset severe paraparesis and bowel/bladder dysfunction. Magnetic resonance imaging of the thoracic and lumbosacral spine showed acute intramedullary hemorrhage in the conus medullaris surrounded by spinal cord congestion extending to T8, with perimedullary flow voids along the ventral and dorsal cord surfaces. Magnetic resonance angiography and spinal angiography confirmed the presence of a SEAVF with a large lumbosacral epidural venous lake supplied by dorsal somatic branches of bilateral L4 segmental arteries. Initially, the intradural venous drainage had been misinterpreted as a single route. The patient underwent surgical interruption of the dilated intradural draining vein after embolization of the feeding vessels. Another small intradural venous drainage route was found on the follow-up angiogram. The second operation with occlusion of the initial part of the epidural venous lake was sufficient to cure this lesion. CONCLUSIONS: With the significant improvement of our patient after treatment of the SEAVF, we speculated that the intramedullary hemorrhage, which had occurred in the area of spinal cord edema, might have resulted from severe venous hypertension, rather than hemorrhagic infarction of the spinal cord. Careful evaluation of the angioarchitecture of SEAVFs is imperative to determine the most effective treatment modality.


Assuntos
Fístula Arteriovenosa/cirurgia , Malformações Vasculares do Sistema Nervoso Central/complicações , Hematoma Epidural Espinal/etiologia , Região Lombossacral/irrigação sanguínea , Artérias/diagnóstico por imagem , Malformações Vasculares do Sistema Nervoso Central/diagnóstico por imagem , Espaço Epidural , Hematoma Epidural Espinal/complicações , Hematoma Epidural Espinal/diagnóstico por imagem , Humanos , Região Lombossacral/diagnóstico por imagem , Angiografia por Ressonância Magnética , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Paraparesia/etiologia , Reoperação , Resultado do Tratamento , Doenças da Bexiga Urinária/etiologia , Veias/diagnóstico por imagem , Veias/cirurgia
4.
Plast Reconstr Surg ; 146(3): 276e-282e, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32842100

RESUMO

BACKGROUND: The deep inferior epigastric artery perforator (DIEP) flap is the gold standard in autologous breast reconstruction. When the abdomen is not available, alternative donor sites can be found at the buttock, the lumbar region, or the thighs. These flaps are referred to as second-choice flaps. This study compares the superior gluteal artery perforator (SGAP) flap and the lumbar artery perforator (LAP) flap to the DIEP flap using patient-reported outcomes. METHODS: A retrospective study was performed reviewing the records of 417 women who underwent a free flap breast reconstruction with either a DIEP, an LAP, or an SGAP flap, between 2006 and 2018. Patients were asked to fill out the BREAST-Q questionnaire, and patient-reported outcomes were analyzed and correlated to the demographic information. RESULTS: The response rate was 54.5 percent, with 50 LAP, 153 DIEP, and 25 SGAP flap patients participating. When questioned about their satisfaction with breasts and satisfaction with outcome, all three procedures were rated similarly high. When comparing the physical well-being of the donor site and appearance of the donor site, LAP flap patients reported significantly lower scores than DIEP and SGAP flap patients. CONCLUSIONS: Patients who undergo LAP or SGAP flap breast reconstruction seem similarly satisfied with the appearance and outcome of their free flap breast reconstruction compared with DIEP flap patients. The donor-site morbidity and its impact on the patient's well-being in SGAP and LAP flap patients have been underestimated. Despite more donor-site discomfort, the LAP and SGAP flaps are feasible alternatives whenever the DIEP flap is not possible.


Assuntos
Neoplasias da Mama/cirurgia , Mamoplastia/métodos , Medidas de Resultados Relatados pelo Paciente , Retalho Perfurante/irrigação sanguínea , Adulto , Artérias , Nádegas/irrigação sanguínea , Nádegas/cirurgia , Artérias Epigástricas , Feminino , Humanos , Região Lombossacral/irrigação sanguínea , Região Lombossacral/cirurgia , Pessoa de Meia-Idade , Estudos Retrospectivos
5.
Plast Reconstr Surg ; 145(4): 706e-714e, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-32221200

RESUMO

BACKGROUND: The lumbar artery perforator flap is an excellent free flap for breast reconstruction whenever the deep inferior epigastric perforator (DIEP) flap is not an option. The main indication is a lack of abdominal bulk, often seen in young BRCA-positive women seeking prophylactic amputation and immediate reconstruction. METHODS: Between October of 2010 and July of 2016, a total of 661 free flap breast reconstructions were performed. The authors retrospectively analyzed patient demographics, perioperative parameters, and secondary corrections. RESULTS: Seventy-six lumbar artery perforator flaps were retained and compared with a cohort of 560 DIEP flaps. The average body mass index for lumbar patients was 23.8 kg/m, with a mean age at operation of 46.3 years. Average body mass index for DIEP patients was 25.2 kg/m, with a mean age at operation of 48.8 years old. Lumbar artery perforator flap weight was 504 g (range, 77 to 1216 g) on average versus 530 g (range, 108 to 1968 g) for the DIEP flaps. The amount of corrective procedures performed was very similar in both cohorts: 13 percent of the lumbar artery perforator and 12 percent of the DIEP patients underwent no procedures, 62 percent in both groups underwent one procedure, and 25 percent versus 27 percent underwent two or more procedures. Lipofilling was performed in 48 percent of lumbar artery perforator flaps compared with 57 percent of the DIEP flaps (p = 0.14). Mean volume injected was 98.0 cc and 125.1 cc for lumbar artery perforator and DIEP flaps, respectively (p = 0.071). CONCLUSIONS: The lumbar flap is a good alternative whenever a DIEP flap is not possible. Bilateral autologous reconstruction is possible even in very thin patients, and secondary corrections are comparable to those for the DIEP.


Assuntos
Mamoplastia/métodos , Retalho Perfurante/transplante , Complicações Pós-Operatórias/epidemiologia , Adulto , Neoplasias da Mama/cirurgia , Artérias Epigástricas/transplante , Feminino , Seguimentos , Sobrevivência de Enxerto , Humanos , Região Lombossacral/irrigação sanguínea , Mamoplastia/efeitos adversos , Mamoplastia/normas , Mastectomia/efeitos adversos , Pessoa de Meia-Idade , Retalho Perfurante/efeitos adversos , Retalho Perfurante/irrigação sanguínea , Retalho Perfurante/normas , Complicações Pós-Operatórias/etiologia , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Resultado do Tratamento
6.
AJNR Am J Neuroradiol ; 40(12): 2010-2015, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31753838

RESUMO

BACKGROUND AND PURPOSE: Although considerable variability exists as to the overall caliber of radiculomedullary arteries, dominant radiculomedullary arteries such as the artery of Adamkiewicz exist. The existence of a great posterior radiculomedullary artery has attracted little attention and has been a matter of debate. The aim of this anatomic study was to determine the presence or absence of the great posterior radiculomedullary artery. MATERIALS AND METHODS: We performed microsurgical dissection on formaldehyde-fixed cadaveric human spinal cords. The artery of Adamkiewicz in the spinal cord specimens (n = 50) was injected with colored latex until the small-caliber arterial vessels were filled and the great posterior radiculomedullary artery was identified. The course, diameter, and location of great posterior radiculomedullary artery were documented. RESULTS: A great posterior radiculomedullary artery was identified in 36 (72%) spinal cord specimens. In 11 (22%) specimens, bilateral great posterior radiculomedullary arteries were present. In 13 cases (26%), a unilateral left-sided great posterior radiculomedullary artery was identified. In 11 cases (22%), a unilateral right-sided great posterior radiculomedullary artery was identified. In 1 specimen (2%), 3 right-sided great posterior radiculomedullary arteries were noted. The average size of the great posterior radiculomedullary arteries was 0.44 mm (range, 0.120-0.678 mm on the left and 0.260-0.635 mm on the right). CONCLUSIONS: A great posterior radiculomedullary artery is present in most (72%) individuals. The authors describe the microsurgical anatomy of the great posterior radiculomedullary artery with emphasis on its morphometric parameters as well as its implications for spinal cord blood supply. Variations of the arterial supply to the dorsal cord are of great importance due to their implications for ischemic events, endovascular procedures, and surgical approaches.


Assuntos
Artérias/anatomia & histologia , Medula Espinal/anatomia & histologia , Adulto , Idoso , Artérias/anormalidades , Cadáver , Feminino , Humanos , Região Lombossacral/anatomia & histologia , Região Lombossacral/irrigação sanguínea , Masculino , Microdissecção , Pessoa de Meia-Idade , Fluxo Sanguíneo Regional , Medula Espinal/irrigação sanguínea , Adulto Jovem
7.
World Neurosurg ; 132: e403-e408, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31476457

RESUMO

BACKGROUND: We compared left and right vascular anatomy at the L5-S1 disc space and validated the anatomical feasibility of the right oblique approach for L5-S1 oblique lumbar interbody fusion. METHODS: Axial T2-weighted magnetic resonance imaging studies at the L5-S1 disc level were used to study 274 subjects (164 women and 110 men; average age, 62.97 years). The distance from the center of the L5-S1 disc to the medial wall of the left or right vessel was measured. Using the vessel position, 3 groups were established: medial, middle, and lateral. To describe the morphological configuration, the vessel type and the presence of perivascular adipose tissue (PVAT) around the vessels were identified on both sides. RESULTS: The vessels on the left L5-S1 disc space were located 12.47 mm from the midline and most subjects (209 subjects; 76.3%) were included in the medial or middle group. On the right side, the vessels were located more laterally (16.93 mm; P = 0.000) and most subjects (248 subjects; 90.5%) were in the middle or lateral group. On the left side, vessels were mostly veins (260 subjects; 94.9%) and 139 subjects (50.7%) had PVAT. On the right side, the vessels were mostly arteries (213 subjects; 77.7%) and 242 (88.3%) had PVAT. CONCLUSIONS: The vessels on the right side of the L5-S1 disc were located more laterally, and most vessels on the right side were arteries accompanying PVAT, which might minimize vessel manipulation. These results indicate that the right side of the L5-S1 disc could provide feasible access for oblique lumbar interbody fusion at L5-S1.


Assuntos
Região Lombossacral/irrigação sanguínea , Fusão Vertebral/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Viabilidade , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Adulto Jovem
8.
J Therm Biol ; 83: 1-7, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31331507

RESUMO

Spinal cord ischemia can result from cardiac arrest. It is an important cause of severe spinal cord injury that can lead to serious spinal cord disorders such as paraplegia. Hypothermia is widely acknowledged as an effective neuroprotective intervention following cardiac arrest injury. However, studies on effects of hypothermia on spinal cord injury following asphyxial cardiac arrest and cardiopulmonary resuscitation (CA/CPR) are insufficient. The objective of this study was to examine effects of hypothermia on motor deficit of hind limbs of rats and vulnerability of their spinal cords following asphyxial CA/CPR. Experimental groups included a sham group, a group subjected to CA/CPR, and a therapeutic hypothermia group. Severe motor deficit of hind limbs was observed in the control group at 1 day after asphyxial CA/CPR. In the hypothermia group, motor deficit of hind limbs was significantly attenuated compared to that in the control group. Damage/death of motor neurons in the lumbar spinal cord was detected in the ventral horn at 1 day after asphyxial CA/CPR. Neuronal damage was significantly attenuated in the hypothermia group compared to that in the control group. These results indicated that therapeutic hypothermia after asphyxial CA/CPR significantly reduced hind limb motor dysfunction and motoneuronal damage/death in the ventral horn of the lumbar spinal cord following asphyxial CA/CPR. Thus, hypothermia might be a therapeutic strategy to decrease motor dysfunction by attenuating damage/death of spinal motor neurons following asphyxial CA/CPR.


Assuntos
Parada Cardíaca/complicações , Hipotermia Induzida/métodos , Isquemia/terapia , Neurônios Motores/fisiologia , Paraplegia/terapia , Animais , Reanimação Cardiopulmonar/efeitos adversos , Parada Cardíaca/terapia , Isquemia/etiologia , Região Lombossacral/irrigação sanguínea , Região Lombossacral/fisiopatologia , Masculino , Paraplegia/etiologia , Ratos , Ratos Sprague-Dawley
9.
Clin Radiol ; 74(10): 756-762, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31300211

RESUMO

The lumbar artery perforator (LAP) flap is a relatively new procedure that can be utilized to manage lumbosacral defects in addition to reconstructing distal body parts as well, such as breast reconstruction. This fasciocutaneous flap is designed based on the LAPs small arteries that emerge from the lumbar arteries then move superficially piercing overlying tissues to perforate the lumbar fascia and supply the skin and subcutaneous tissue; However, anatomical and clinical studies regarding the LAP flap and its perforators are sparse in the literature, and the results are even contradicting. This article will discuss the LAP flap, the anatomy of its perforators, and the clinical aspects about its usage. In addition, we explore its preoperative imaging evaluation, and deliver a guide on image reporting and radiological data that will benefit the surgeon most during the procedure.


Assuntos
Região Lombossacral/irrigação sanguínea , Retalho Perfurante/irrigação sanguínea , Artérias/anatomia & histologia , Artérias/diagnóstico por imagem , Angiografia por Tomografia Computadorizada , Humanos , Imageamento Tridimensional , Região Lombossacral/diagnóstico por imagem , Cuidados Pré-Operatórios
10.
Pain Physician ; 22(3): E225-E232, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-31151345

RESUMO

BACKGROUND: The detailed structure of the lumbar intervertebral foramina has been well-studied. Nevertheless, detailed descriptions of branches of the intervertebral vein (IV) through the lumbar intervertebral foramina are lacking. OBJECTIVES: This study aimed to provide an anatomical basis for invasive treatment targeting the branches of the IV using an approach through the lumbar intervertebral foramina, particularly for the purposes of transforaminal epidural steroid injection. STUDY DESIGN: This research involved a dissection-based study of 10 embalmed human cadavers. SETTING: The research took place at The Third Affiliated Hospital of Southern Medical University. METHODS: One hundred lumbar intervertebral foramina from 10 embalmed cadavers were studied. Branches of the IV in the intervertebral foramina were observed. The length and diameter of the veins were measured using a Vernier caliper. RESULTS: At a rate of 100%, branches of the IV were observed in the 100 lumbar foramina examined in our study. The following 4 types of branches of the IV were routinely found: Type I in 27 (27%) of the IV foramina, in which a superior branch of the IV ran along the inferior margin of the vertebral pedicle; Type II in 18 (18%) of the intervertebral foramina, in which an inferior branch of the IV ran along the superior margin of the inferior vertebral pedicle; Type III in 41 (41%) of the intervertebral foramina, in which the IV was divided into a superior and inferior branch; and Type IV in 14 (14%) of the intervertebral foramina, in which the IV was divided into 2 superior branches and an inferior branch. LIMITATIONS: The greatest weakness of this study is that it lacks actual clinical verification. Future clinical trials are expected to contribute more objective data concerning the IV branches. Due to the relative changes in vascular position during dissection, the relevant data warrant improvement. CONCLUSIONS: The lumbar IVs are an important part of the anatomical structure of the intervertebral foramina. Adequate knowledge of the IV may be of clinical importance to physicians performing transforaminal epidural steroid injection. KEY WORDS: Clinical anatomy, intervertebral veins, lumbar vertebra, Kambin's triangle, safe triangle, intervertebral foramina, vertebral venous system, inadvertent injection, transforaminal epidural steroid injection.


Assuntos
Vértebras Lombares/irrigação sanguínea , Veias/anatomia & histologia , Cadáver , Feminino , Humanos , Região Lombossacral/irrigação sanguínea , Masculino
11.
PLoS One ; 14(3): e0213164, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30835754

RESUMO

To observe the regional anatomy of the lumbar artery (LA) associated with the extrapedicular approach applied during percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP), we collected 78 samples of abdominal computed tomography angiography imaging data. We measured the nearest distance from the center of the vertebral body puncture point to the LA (distance VBPP-LA, DVBPP-LA). According to the DVBPP-LA, four zones, Zone I, Zone II, Zone III and Zone IV, were identified. LAs that passed through these zones were called Type I, Type II, Type III and Type IV LAs, respectively. A portion of the lumbar vertebrae had an intersegmental branch that originated from the upper segmental LA and extended longitudinally across the lateral wall of the pedicle; it was called Type V LA. Compared with the DVBPP-LA in L1, L2, L3 and L4, the overall difference and between-group differences were significant (P < 0.05). In L1, L2, L3, L4 and L5, there were 8, 4, 4, 0 and 1 Type I LAs, respectively. There were no Type V LAs in L1 and L2, but there were 2, 16 and 26 Type V LAs in L3, L4 and L5, respectively. In L1-L5, the numbers of Type I LA plus Type V LA were 8, 4, 6, 16 and 27, and the presence ratios were 5.1%, 2.6%, 5.6%, 10.3% and 17.3%, respectively. In L4 and L5, the male presence ratios of Type I LA plus Type V LA were 7.1% and 10.7%, respectively, and the female presence ratios were 13.9% and 25.0%, respectively. Thus, extrapedicular PVP (PKP) in lumbar vertebrae had a risk of LA injury and was not suggested for use in L4 and L5, especially in female patients.


Assuntos
Artérias/anatomia & histologia , Abdome/diagnóstico por imagem , Adulto , Idoso , Angiografia por Tomografia Computadorizada , Feminino , Humanos , Região Lombossacral/irrigação sanguínea , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fraturas da Coluna Vertebral/cirurgia , Vertebroplastia , Adulto Jovem
12.
J. bras. nefrol ; 41(1): 89-94, Jan.-Mar. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1002420

RESUMO

Abstract Introduction: Vascular access (VA) in hemodialysis (HD) is essential to end-stage renal disease (ESRD) patients survival. Unfortunately, after some years in HD program, a significant number of patients may develop VA failure for many reasons. In this situation, arterial venous fistula (AVF) confection or catheters placement in traditional vascular sites (jugular, femoral or subclavian) are not feasible. In this scenario, translumbar tunneled dialysis catheter (TLDC) may be a salvage option. Objectives: To describe placement technic, complications, and patency of 12 TLDC. Methods: A retrospective study was performed to analyze 12 TLDC placement in an angiography suite using fluoroscopic guidance at the University Hospital of the Rio Grande do Norte Federal University from January 2016 to October 2017. The data collected of the total procedures performed consisted of demographic characteristics, success rates, observed complications, patient survival, and catheter patency. Results: All 12 TLDC were placed with success; there were only 2 significant periprocedure complications (major bleeding and extubation failure); 41.6% of patients presented a catheter-related first infection after 98 ± 72.1 (6-201) days, but catheter withdrawal was not necessary, mean total access patency was 315.5 (range 65 - 631) catheter-days, and catheter patency at 3, 6 and 12 months was 91 %, 75%, and 45%. Conclusion: TLDC is an option for patients with VA failure, improving survival and acting as a bridge for renal transplantation.


Resumo Introdução: O acesso vascular (AV) para hemodiálise (HD) é crucial para os pacientes portadores de doença renal crônica (DRC) estágio V. Infelizmente, com o passar dos anos, um percentual não desprezível desses enfermos evolui para falência de AV por diversos motivos, o que impossibilita a confecção de novas fístulas arteriovenosas (FAV) ou o implante de cateteres venosos centrais nos sítios de punções tradicionais. Nesse cenário, o implante de cateteres translombares para hemodiálise (CTLHD) em veia cava inferior ganha destaque como medida salvadora. Objetivos: Relatar uma série de 12 casos de implante de CTLHD, sua técnica de implante, patência e complicações. Métodos: Estudo retrospectivo que analisou 12 implantes de CTLHD por radiologista intervencionista no setor de hemodinâmica do Hospital Universitário da Universidade Federal do Rio Grande do Norte (UFRN), no período de janeiro/2016 a outubro/2017. Os dados coletados consistiram em: características demográficas da população estudada, taxa de sucesso, complicações observadas, sobrevida dos pacientes, patência do cateter e desfechos clínicos. Resultados: Todos os 12 CTLHD foram implantados e utilizados com sucesso; ocorreram apenas 2 complicações associadas ao procedimento (sangramento e falha na extubação); 41,6% dos pacientes apresentaram infecção relacionada ao cateter após 98 ± 72,1 dias (6-201 dias), mas não houve necessidade de remoção; e a patência foi de 315,5 cateteres-dia (65-631 dias). Conclusão: O CTLHD é uma opção para pacientes com falência de acesso vascular, prolongando a sobrevida dos pacientes e atuando como ponte para o transplante renal.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Doenças Vasculares/etiologia , Veia Cava Inferior/cirurgia , Cateterismo Venoso Central/métodos , Cateteres de Demora/efeitos adversos , Diálise Renal , Cateteres Venosos Centrais/efeitos adversos , Falência Renal Crônica/terapia , Região Lombossacral/irrigação sanguínea , Fluoroscopia , Estudos de Viabilidade , Estudos Retrospectivos , Fístula Arteriovenosa/complicações , Transplante de Rim , Resultado do Tratamento , Hemorragia/etiologia
13.
World Neurosurg ; 125: e435-e441, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30708080

RESUMO

OBJECTIVE: To observe anatomic relationships between lumbar bicortical pedicle screws (BPSs) at 2 sagittal section angles (SSAs) and lumbar artery (LA). METHODS: We observed 2 SSAs, vertical angle and cephalic angle, of the BPS. The positions at which the BPS breaks through the anterior vertebral cortex were defined as point A and point B. Distances from point A and point B to LAs were measured. The percentage of risk of injury to LAs was calculated according to these distances. RESULTS: At the same transverse section angle on the left and right side in L1 and L2, distance from point A to LA was significantly greater than distance from point B to LA (P < 0.001) except at a transverse section angle of 0° on the right side in L2 (P > 0.05). At the same transverse section angle on the left in L3 and L4, distance from point B to LA was significantly greater than distance from point A to LA (P < 0.001). The percentages of high risk of injury to the LA resulting from BPSs at the vertical angle in L1 and L2 were 0%-6.2%. The percentages of high risk of injury to the LA resulting from BPSs at the cephalic angle on the left side in L3 and L4 were 0%-18.5%. CONCLUSIONS: Lumbar BPSs present a risk of injury to the LA. The vertical angle is the recommended SSA for BPSs in L1 and L2, and the cephalic angle is the recommended SSA in L3 and L4.


Assuntos
Vértebras Lombares/cirurgia , Região Lombossacral/irrigação sanguínea , Região Lombossacral/cirurgia , Parafusos Pediculares , Idoso , Feminino , Humanos , Vértebras Lombares/irrigação sanguínea , Masculino , Pessoa de Meia-Idade , Risco , Medula Espinal/irrigação sanguínea , Medula Espinal/cirurgia , Fusão Vertebral/métodos
14.
Eur J Cardiothorac Surg ; 56(1): 126-134, 2019 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-30668733

RESUMO

OBJECTIVES: Minimally invasive staged segmental artery coil- and plug embolization (MIS2ACE) has been introduced for spinal cord injury prevention prior to open or endovascular thoraco-abdominal aortic aneurysm repair. To date, no optimal pattern has been developed. The aim of this study was to identify the optimal MIS2ACE occlusion pattern. METHODS: Twenty-five juvenile pigs were randomly assigned to 3 MIS2ACE occlusion patterns (2 stages) and a control group [single-stage segmental artery (SA) occlusion, N = 7]. The first pattern started with occlusion of all lumbar segmental arteries in the first stage and the remaining thoracic arteries in the second stage (regional pattern, N = 6). In group 2, an alternating approach with occlusion of every other SA in the first stage and the remainder in the second stage was used (alternating pattern, N = 6). The third pattern started with occluding the watershed area between thoracic level 12 and lumbar level 2 in the first stage and the remaining arteries in the second stage (watershed pattern, N = 6). Neurological assessment at 6-h intervals and spinal cord tissue perfusion measurements via microspheres at 6 time points were performed. At the end of the experiments, the spinal cord was histopathologically examined. RESULTS: An average of 6 ± 2 coils were used per SA. In the control group a total of 57% (N = 4) of animals experienced permanent paraplegia, 1 animal (16%) of the alternating and watershed intervention group suffered from permanent paraplegia. Animals from the staged regional pattern did not experience permanent paraplegia. Furthermore, no evidence of significant tissue damage was observed (P < 0.05 vs control). Tissue perfusion of the lumbar spinal cord in the regional pattern group recovered within 3 days after the second stage to 89.2 ± 47 percent-of-baseline (P = 0.393), whereas mean perfusion of the other 2 intervention groups and the control remained significantly lower compared to the baseline (35.7 ± 16%, 30.2 ± 11% and 63.2 ± 19, P < 0.05). CONCLUSIONS: This study provides evidence that MIS2ACE (minimally invasive staging) may result in less ischaemic spinal cord injury and favourable neurological outcomes compared to complete (1 stage) SA occlusion. A regional-based occlusion pattern (starting with the lumbar segmental arteries) seems to be the best 2-stage approach.


Assuntos
Aorta/cirurgia , Embolização Terapêutica , Procedimentos Cirúrgicos Minimamente Invasivos , Animais , Aneurisma Aórtico/cirurgia , Modelos Animais de Doenças , Embolização Terapêutica/efeitos adversos , Embolização Terapêutica/métodos , Feminino , Região Lombossacral/irrigação sanguínea , Procedimentos Cirúrgicos Minimamente Invasivos/efeitos adversos , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Paraplegia/prevenção & controle , Complicações Pós-Operatórias/prevenção & controle , Isquemia do Cordão Espinal/prevenção & controle , Suínos
15.
J Bras Nefrol ; 41(1): 89-94, 2019.
Artigo em Inglês, Português | MEDLINE | ID: mdl-30281060

RESUMO

INTRODUCTION: Vascular access (VA) in hemodialysis (HD) is essential to end-stage renal disease (ESRD) patients survival. Unfortunately, after some years in HD program, a significant number of patients may develop VA failure for many reasons. In this situation, arterial venous fistula (AVF) confection or catheters placement in traditional vascular sites (jugular, femoral or subclavian) are not feasible. In this scenario, translumbar tunneled dialysis catheter (TLDC) may be a salvage option. OBJECTIVES: To describe placement technic, complications, and patency of 12 TLDC. METHODS: A retrospective study was performed to analyze 12 TLDC placement in an angiography suite using fluoroscopic guidance at the University Hospital of the Rio Grande do Norte Federal University from January 2016 to October 2017. The data collected of the total procedures performed consisted of demographic characteristics, success rates, observed complications, patient survival, and catheter patency. RESULTS: All 12 TLDC were placed with success; there were only 2 significant periprocedure complications (major bleeding and extubation failure); 41.6% of patients presented a catheter-related first infection after 98 ± 72.1 (6-201) days, but catheter withdrawal was not necessary, mean total access patency was 315.5 (range 65 - 631) catheter-days, and catheter patency at 3, 6 and 12 months was 91 %, 75%, and 45%. CONCLUSION: TLDC is an option for patients with VA failure, improving survival and acting as a bridge for renal transplantation.


Assuntos
Cateterismo Venoso Central/métodos , Cateteres de Demora/efeitos adversos , Cateteres Venosos Centrais/efeitos adversos , Falência Renal Crônica/terapia , Região Lombossacral/irrigação sanguínea , Diálise Renal , Doenças Vasculares/etiologia , Veia Cava Inferior/cirurgia , Adulto , Idoso , Fístula Arteriovenosa/complicações , Estudos de Viabilidade , Feminino , Fluoroscopia , Hemorragia/etiologia , Humanos , Transplante de Rim , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento
16.
J Neurointerv Surg ; 11(1): 95-98, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30166334

RESUMO

BACKGROUND AND PURPOSE: Thoracolumbar and sacral spinal epidural arteriovenous fistulas (SEDAVFs) are an increasingly recognized form of spinal vascular malformation. The purpose of this study was to perform a systematic review of the demographics, clinical presentation and treatment results of thoracolumbar SEDAVFs. MATERIALS AND METHODS: Pubmed, Scopus and Web of Science databases were searched from January 2000 to January 2018 for articles on treatment of SEDAVFs. Pooled data of individual patients were analyzed for demographic and clinical features of SEDAVFs as well as treatment outcomes. RESULTS: There were 125 patients from 11 studies included. Mean age was 63.5 years. There was a male sex predilection (69.6%). Sensory symptoms including pain or numbness were the most frequently presenting symptoms. Fistula location was the lumbosacral spine in 79.2% and the thoracic spine in 20.8%. Involvement of intradural venous drainage was more common than extradural venous drainage only (89.6% vs 10.4%). Of the 123 treated patients, endovascular therapy was performed in 67.5% of patients, microsurgery in 23.6%, and combined treatment in 8.9%. The overall complete obliteration rate was 83.5% and did not differ between groups. Clinical symptoms improved in 70.7% of patients, were stable in 25%, and worsened in 1.7% with no difference between treatment modalities. CONCLUSIONS: Thoracic and lumbosacral SEDAVFs often present with symptoms secondary to congestive myelopathy or compressive symptoms. Both endovascular and microsurgical treatments were associated with high obliteration rates and good clinical outcomes.


Assuntos
Fístula Arteriovenosa/diagnóstico por imagem , Região Lombossacral/irrigação sanguínea , Região Lombossacral/diagnóstico por imagem , Sacro/irrigação sanguínea , Sacro/diagnóstico por imagem , Artérias Torácicas/diagnóstico por imagem , Idoso , Fístula Arteriovenosa/terapia , Embolização Terapêutica/métodos , Espaço Epidural/irrigação sanguínea , Espaço Epidural/diagnóstico por imagem , Feminino , Humanos , Masculino , Microcirurgia/métodos , Pessoa de Meia-Idade , Doenças da Coluna Vertebral/diagnóstico por imagem , Doenças da Coluna Vertebral/terapia , Resultado do Tratamento
17.
Eur J Cardiothorac Surg ; 55(4): 646-652, 2019 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-30428029

RESUMO

OBJECTIVES: Our goal was to identify anatomical and physiological factors that could predict the amount of cerebrospinal fluid (CSF) drainage in patients undergoing elective endovascular repair of descending thoracic and thoracoabdominal aortic disease. METHODS: All consecutive elective endovascular procedures performed for descending thoracic or thoracoabdominal aortic disease between January 2015 and December 2017 were included in the study. Routine use of CSF drainage was established in all patients. The goal of drainage was to reach a spinal fluid pressure of 10-12 mmHg by draining in 5-15-ml aliquots. The number of visible intercostal and lumbar segmental arteries (SAs) was evaluated before and after endovascular repair. The covering ratio of SAs was calculated as covered preoperative SAs/total preoperative SAs. RESULTS: Twenty-four consecutive patients were included in the final analysis. The indication for the intervention was a descending thoracic aneurysm in 13 cases, a thoracoabdominal aneurysm in 4 cases and a chronic type B dissection in 7 cases. The procedure performed was thoracic endovascular aortic repair in 20 cases and fenestrated endovascular aneurysm repair in 4 cases. None of the patients developed spinal cord ischaemia. The mean volume of CSF drained was 46 ml. The mean length of aortic coverage was 231 mm. The mean number of total preoperative SAs and of covered preoperative SAs was, respectively, 22 and 9. The volume of CSF drained was significantly correlated with all these variables (length of aortic coverage, total visible SAs and covered SAs), but the most powerful correlation was individuated with the covering ratio of SAs. CONCLUSIONS: Our findings suggest that the percentage of intercostal and lumbar SAs covered by placement of a stent graft can predict the volume of CSF drained in patients undergoing elective endovascular repair of descending thoracic and thoracoabdominal aortic disease.


Assuntos
Doenças da Aorta/cirurgia , Vazamento de Líquido Cefalorraquidiano/etiologia , Procedimentos Endovasculares/métodos , Artérias Torácicas/patologia , Idoso , Idoso de 80 Anos ou mais , Aorta Torácica/cirurgia , Aneurisma da Aorta Torácica/cirurgia , Prótese Vascular , Implante de Prótese Vascular/efeitos adversos , Implante de Prótese Vascular/métodos , Procedimentos Endovasculares/efeitos adversos , Feminino , Humanos , Região Lombossacral/irrigação sanguínea , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Stents , Artérias Torácicas/fisiopatologia
18.
J Emerg Med ; 55(4): 544-546, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-30037517

RESUMO

BACKGROUND: Compartment syndrome is a life-threatening complication of traumatic injury, most commonly, direct trauma. Back pain is a common cause of visits to the emergency department (ED) and often is treated without imaging or diagnostic testing. Lumbar paraspinal compartment syndrome is a rare cause of acute back pain. CASE REPORT: A 43-year-old woman presented to the ED after direct trauma to the lower back. Laboratory studies revealed rhabdomyolysis and acute kidney injury, with examination findings and imaging consistent with lumbar paraspinal compartment syndrome. She was taken to the operating room for emergent fasciotomy. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: It is the job of the emergency physician to identify the red flags in history and physical examination that warrant further diagnostic testing. Early diagnosis and surgical consultation is the key in avoiding morbidity and achieving good outcomes in all forms of compartment syndrome.


Assuntos
Síndromes Compartimentais/diagnóstico , Região Lombossacral/irrigação sanguínea , Acidentes por Quedas , Adulto , Analgésicos Opioides/uso terapêutico , Anti-Inflamatórios não Esteroides/uso terapêutico , Dor nas Costas/tratamento farmacológico , Síndromes Compartimentais/etiologia , Síndromes Compartimentais/cirurgia , Feminino , Humanos , Ibuprofeno/uso terapêutico , Cetorolaco/uso terapêutico , Região Lombossacral/anormalidades , Morfina/uso terapêutico , Obesidade Mórbida/complicações , Músculos Paraespinais/anormalidades , Músculos Paraespinais/lesões , Tomografia Computadorizada por Raios X/métodos
19.
Plast Reconstr Surg ; 142(1): 1e-8e, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29952885

RESUMO

BACKGROUND: The lumbar artery perforator flap is an alternative flap in breast reconstruction for those patients who are not eligible for a deep inferior epigastric artery perforator (DIEAP) flap. Shaping of this flap is easier compared with other flaps because of the quality of the lumbar fat and the gluteal extension. METHODS: Between October of 2010 and June of 2017, a total of 100 lumbar artery perforator free flap breast reconstructions were performed in 72 patients. Patient demographics, indications, flap specifics, and complications were reviewed retrospectively. RESULTS: Twenty-eight bilateral and 44 unilateral breast reconstructions with a lumbar artery perforator flap were performed. Mean patient age was 48 years, and the average body mass index was 23.11 kg/m. The authors report 43 preventive mastectomies for elevated cancer risk with subsequent immediate reconstruction, 34 secondary reconstructions, and 14 tertiary reconstructions. Mean operative time was 7 hours 4 minutes, including the mastectomy in primary cases. Mean flap weight was 499 g (range, 77 to 1216 g) and mean follow-up time was 30 months. The revision rate was 22 percent and nine flaps were lost. CONCLUSIONS: The lumbar artery perforator flap is a valuable alternative to the DIEAP flap in breast reconstructive surgery. It is an excellent flap for BRCA-positive patients who are typically young and have limited excess tissue at the conventional donor sites. Despite higher revision rates compared with the DIEAP flap, the lumbar flap is superior in mimicking the shape and feel of native breast tissue. Scarring at the donor site remains a sore point but can be easily treated and used to an advantage to contour the flanks. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.


Assuntos
Retalhos de Tecido Biológico/irrigação sanguínea , Mamoplastia/métodos , Retalho Perfurante/irrigação sanguínea , Adulto , Idoso , Artérias , Feminino , Seguimentos , Retalhos de Tecido Biológico/transplante , Humanos , Região Lombossacral/irrigação sanguínea , Mastectomia , Pessoa de Meia-Idade , Avaliação de Resultados em Cuidados de Saúde , Retalho Perfurante/transplante , Estudos Retrospectivos
20.
Microsurgery ; 38(7): 752-757, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-29953654

RESUMO

BACKGROUND: Repair of large soft tissue defects in meningomyelocele is difficult and its morbidity is high. By applying unilateral lumbar artery perforator transposition flap for closing these defects, we aimed to investigate effects on the repair procedure, duration of surgery and recovery period, with the rates of bleeding and morbidity. PATIENTS AND METHODS: Our report was conducted in 38 patients between the years 2013 and 2017. All soft tissue defects were repaired with unilateral lumbar artery perforator flap (LAPF) in meningomyelocele. Fourteen patients were female and 24 patients were male. The youngest patient was a 5.5 month premature female baby and weighing 570 g. The oldest was weighing 3,700 g and at 1.5 months old. RESULTS: Mean flap size was 32 ± 29.4 cm2 (ranged: 4 × 3-8 × 7 cm2 ). The mean rotation angle was 126.7° (ranged: 90°-170°). Flap positions were separated as 9 (23%) thoracodorsal and 29 (77%) lumbosacral. None of the patients had flap necrosis, infection, or hematoma. The operation took 23 ± 5.3 minutes on average and bleeding was minimal as 16 cc. All patients were discharged within around 9 ± 2 days. The follow-up period of the patient ranged from 4 to 21 months. Flap survival was at the rate of 100%. There was no flap or postoperative complications. Final outcome for all patients were assessed as complete healing. All patients recovered fast with minimal blood lose, and satisfied the outcomes. CONCLUSIONS: As a result, unilateral lumbar perforator flap can be performed successfully in every center. This report suggests using LAPF for reconstruction of meningomyelocele by surgeons as a safe and reliable option, allowing surgeons strong results.


Assuntos
Meningomielocele/cirurgia , Retalho Perfurante/irrigação sanguínea , Procedimentos de Cirurgia Plástica/métodos , Cicatrização/fisiologia , Artérias/cirurgia , Artérias/transplante , Estudos de Coortes , Feminino , Seguimentos , Sobrevivência de Enxerto , Humanos , Lactente , Recém-Nascido , Região Lombossacral/irrigação sanguínea , Masculino , Meningomielocele/diagnóstico , Retalho Perfurante/transplante , Estudos Retrospectivos , Medição de Risco
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